New treatment options for non-metastatic castration resistant (nmCRPC) prostate cancer
DOI: 10.22591/magyurol.2020.2.geczil.58
Authors:
Géczi Lajos dr.
Országos Onkológiai Intézet, Urogenitalis Tumorok és Klinikai Farmakológiai Osztály, Budapest (osztályvezető: Géczi Lajos dr.)
Summary
In this rewiev the author presents the results of SPARTAN, PROSPER and ARAMIS studies in nmCRPC. In the main clinical endponds (MFS, PFS, OS) apalutamid, enzalutamid and darolutamid in combination with androgen deprivation therapy (ADT) showed significant advantage compare to placebo and ADT. After these phase III clinical studies new standard treatment possibilities are available for clinicians in nmCRPC.